Dear Dr. Ellie:
Monosodium phosphate (NaH2PO4) Is said to rebuild teeth?
Many of these toothpaste comparison studies are flawed and often relate to short timelines.
Sodium monofluorophosphate is usually chosen for cost effectiveness (=more profit).
It can be combined with chalk-based products which makes it cheaper to produce – and for these reasons it has been frequently promoted for use in developing countries.
The actual fluoride in this compound is tightly covalent so it requires enzymic hydrolysis to release the fluoride ions for remineralization.
I prefer sodium fluoride paste (Crest Original). The active ingredient cannot be combined with the chalk abrasives. The problem for toothpaste companies is that such formulation is more expensive.
Studies by Bowen 1995 and Volpe 1995 have compared their efficacy – varying results – I will stick with Crest Original with sodium fluoride!
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